The Secretion of Reticulocytes

ER5 Helen W. Belding,M.D., Winston-Salem, N. C. Conrad Maier, M.D., Zurich, Switzerland Sheila T. Callender,M.D.,Oxford, England Milos Netou ek,M.D.,Prague, Czechoslovakia Robert B. Chodos M.D. Framingham Mass. Charles E. Rath, M.D., Washington . . . Jean P. Soulier M.D. Paris France Roger C. Crafts, Ph.D., Cincinnati , RamonM.Su#{225}rez M.D. SanJuan PuertoRrco C. R. DasGupta, M.D., Calcutta, India Timothy R. Talbot, Jr., M.D., New York Solomon Estren, M.D., New York Philip F. Wagley, 1’ I.D., Baltimore Oliver P. Jones, Ph.D., Buffalo Jan Waldenstr#{246}m, M.D., Upsala, Sweden BONE MARROW AND BLOOD FORMATION MYELOID METAPLASIA. ill. Block and L. 0. Jacobson. From the Department of Medicine, University of Chicago, Chicago, Ill. J. A. M. A. 143: 1390-1396, 1950. This review of “mveloid metaplasia” is based on a study of 12 cases in which the diagnosis was made on clinical, hematologic and pathologic grounds; and on study of comparative anatomic, embryologic and experimental considerations of hematopoiesis. “Myeloid metaplasia,” it is pointed out, can l)e diagnosed only by biopsy of liver or spleen, although certain clinical and hematologic features are common to patients with this disorder (weakness , hemorrhagic tendency , leuko-erythroblastic anemia , hepatosplenomegaly) . The bone marrow, it was found, might be fibrotic, hyperplastic or infiltrated with neoplasm. An underlying etiologic disease might he present (tuberculosis, metastatic carcinoma, osteoscierosis, et al.) ; or “myeloid metaplasia” might he idiopathic. The authors consider “rnyeloid metaplasia” to be a nonspecific response of primitive, multipotential cells of the liver and spleen to a variety of stimuli. They stress that this response is fundamentally different from leukemia; whence the importance in differentiation of the two diseases, since treatment and prognosis are different-SE. THE BI ooD OF GASTROPOD MOLLUSCS. W. C. George and J. H. Ferguson. From the Department of Anatomy, University of North Carolina, Chapel Hill, N. C. J. Morphol. 86: 315-327, 1950. The field of comparative hematology is very large and interesting but relatively few papers have been published on this subject within recent years. Material for the present investigation was obtained chiefly from the gastropod mollusc Busycon carica. The circulating blood contains three types of cells: (1) lymphoid cells which are relatively scarce, (2) granular macrophages which are the largest and most numerous and (3) eosinophilie granular amoel)ocytes. Some hemopoiesis takes place intravascularly by mitosis. Plasma turns blue upon exposure to air due to the presence of hemocyanin. Extravasated blood does not coagulate hut the cells agglutinate.-O.P.J. THE TIME FACTOR IN LETHAL EFFECTS OF TOTAL ROENTGEN IRRADIATION IN TRITON. V. V. Brunst and E. A. Sheremetieva-Brunst. From the University of Maryland School of Medicine, Baltimore, Maryland. Am. J. Roentgenol. 62: 550-554, 1949. The authors have exposed adult Tritons (triton cristatus, amphibia, u odela) to equivalent amounts of roentgen radiation in a single or fractional dose. Their results indicate that the lethal effects of the irradiation are related to the total dosage rather than the manner in which it is given.-C.A.F. For personal use only. on October 30, 2017. by guest www.bloodjournal.org From